Associate Scientist I, Molecular and Cell Biology

Company: Avidity Biosciences
Location: San Diego
Posted on: July 13, 2025

Job Description:

Job Title: Associate Scientist I, Molecular and Cell Biology Location: San Diego, CA Position type: FLSA: Full time Exempt Department: Finance ID: Technical Development 3101-101226-BF Profoundly Improve People’s lives by Revolutionizing the Delivery of RNA Therapeutics At Avidity Biosciences, we are passionate about the impact of every employee in realizing our vision of improving people’s lives by delivering a new class of RNA therapeutics. Avidity is revolutionizing the field of RNA with its proprietary AOCs, which are designed to combine the specificity of monoclonal antibodies with the precision of oligonucleotide therapies to address targets and diseases previously unreachable with existing RNA therapies. If you are a committed, solution-oriented thinker, join us in making a difference and become part of our growing culture that is integrated, collaborative, agile and focused on the needs of patients. Avidity Biosciences, Inc.'s mission is to profoundly improve people's lives by delivering a new class of RNA therapeutics - Antibody Oligonucleotide Conjugates (AOCs™). Utilizing its proprietary AOC platform, Avidity demonstrated the first-ever successful targeted delivery of RNA into muscle and is leading the field with clinical development programs for three rare muscle diseases: myotonic dystrophy type 1 (DM1), Duchenne muscular dystrophy (DMD) and facioscapulohumeral muscular dystrophy (FSHD). Avidity is broadening the reach of AOCs with its advancing and expanding pipeline, including programs in cardiology and immunology through internal discovery efforts and key partnerships. Avidity is headquartered in San Diego, CA. For more information about our AOC platform, clinical development pipeline, and people, please visit www.aviditybiosciences.com and engage with us on LinkedIn and X . The Opportunity As Avidity transitions from late stage clinical to commercial operations, an effective quality control strategy will be critical to ensuring the safety, efficacy and reproducibility of our drug products. To facilitate these efforts, we are seeking an Associate Scientist I to join the Analytics group with experience in developing and optimizing robust cell-based assays for later phase clinical programs. The position will also support preclinical development of second-generation AOC therapeutics. This is a unique opportunity and will enable the individual to interact with multiple departments including Chemistry, Biology, and Bioanalytical Sciences. This individual will work in a high-paced matrix environment and must be able to communicate and collaborate between them effectively. What You Will Contribute Excellent laboratory techniques and the ability to work independently Significant experience with mammalian cell culture and cell line development Proficiency with in vitro transfection, dosing, and downstream assays Experience with running ELISA workflows and assistance with creation of new ELISA methods Wet-bench efforts towards analytical assay execution and validation Maintain up to date ELN Ability to communicate data, findings, and next steps to a team with a broad background Some prior experience with assay automation Ability to design and build DNA plasmids and use related software such as Benchling molecular biology suite and/or SNAP gene Flow-cytometry experience A positive can-do attitude; someone that thrives working as a part of a highly productive team What We Seek BA or BS in biology or related discipline with 4-5 years of work experience in biotechnology or a university setting laboratory or an BA/MS degree in biology, bioengineering, cell biology or equivalent with 6 years of industry experience Experience with analytical assay development and qualification Proven ability to thrive and enable success in a cross-functional and collaborative environment. Excellent communication and interpersonal skills and the ability to facilitate constructive and expedient problem-solving. Ability to multi-task, manage conflict, and work efficiently in a fast-paced environment. R or python-based data wrangling skills to facilitate data analysis workflows (preferred but not required) What We Will Provide to You The base salary range for this role is $99,750 – $110,000. The final compensation will be commensurate with such factors as relevant experience, skillset, internal equity and market factors. Avidity offers competitive compensation and benefits, which include the opportunity for annual and spot bonuses, stock options, and RSUs, as well as a 401(k) with an employer match. In addition, the comprehensive wellness program includes coverage for medical, dental, vision, and LTD, and four weeks of time off. A commitment to learning and development which includes a variety of programming internally developed by and for Avidity employees, opportunities for job-specific training offered by industry, and an education reimbursement program.

Keywords: Avidity Biosciences, Bellflower , Associate Scientist I, Molecular and Cell Biology, Science, Research & Development , San Diego, California